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Pharmaceuticals
Mixion - Mixing Technology
Narrow Blade Hydrofoil impellers by Mixion offer excellent flow characteristics, generate an axial flow and are best suited as pharmaceutical mixers. These pharmaceutical agitators not only offer good mixing but are also the most efficient agitators in terms of power consumption.
Pharmaceutical Agitators
Narrow Blade Hydrofoil impellers by Mixion offer excellent flow characteristics, generate an axial flow and are best suited as pharmaceutical mixers. These pharmaceutical agitators not only offer good mixing but are also the most efficient agitators in terms of power consumption.
Casestudy : Power Savings
Over the years, we have successfully replaced traditional impeller systems with Hydrofoil impellers and benefited various API manufacturing companies. One such example is of an API manufacturing site at Vishakhapatnam, Andhra Pradesh which benefitted with massive energy savings because of our hydrofoil impeller installation.
- No. of reactor agitators changed: 38
- Pre-Modification consumed power: 342 kW
- Post-Modification consumed power: 94 kW
Annual Savings (Rs. Million): ~11
Pay Back <18 months
The application of these 38 reactors representing typical API applications and its energy savings is illustrated as under:
| Sr. No. | Vessel Capacity (m3) | Application | Installed Power with Anchor (HP) | Installed Power with High Efficiency Agitator (HP) | Actual Running Hours/Day | Actual Saving Unit/Day | Pay back in Months |
|---|---|---|---|---|---|---|---|
| 1 | 2 | Dissolution | 7,5 | 3 | 22 | 92,5 | 14 |
| 2 | 3 | Grignard Reaction | 10 | 5 | 22 | 129.5 | 10.8 |
| 3 | 5 | Solvent Distillation | 12.5 | 5 | 16.5 | 105.7 | 14.2 |
| 4 | 7,5 | Solvent Distillation | 15 | 5 | 23 | 238.1 | 7.5 |
| 5 | 8 | Layer Separation Washing | 15 | 5 | 22 | 187.9 | 9.4 |
| 6 | 10 | Layer Separation Washing | 15 | 5 | 16.5 | 145.2 | 14.7 |
Special Duty Agitators
The API manufacturing also involves a typical dry distillation / co-distillation, where the objective is to distil off base solvent to absolute dryness of solid precipitate. Anchors often aren’t designed with adequate torque to keep mass in motion. Mixion’s helical impeller is a recommended choice for such demanding mixing.
For instance, at an API manufacturing unit in Hyderabad, Telangana the manufacturing of Metformin HCl had a processing stage where the solvent from reaction mass needed to be stripped off on which anchor agitators weren’t performing. These, once replaced with our helical impeller, resulted in higher yield and purity of the end product.
